http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0597018-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_191da2a7da3f78be60f36cabc37e7c44 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J17-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-256 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J17-00 |
| filingDate | 1992-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_641b87b47eaa6905486ab32d703cfcf9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cc20160cc7de4277c42a1b69ea0a0c5 |
| publicationDate | 1994-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0597018-A1 |
| titleOfInvention | Novel glycoside compounds and production and use thereof |
| abstract | New glycosides, in particular steroidal and nonsteroidal glycosides, and new production methods. The new process for producing the new glycosides involves glycosylating aglycon compounds with tri-O-acyl glucal using molecular or ionized halogen as the reaction catalyst. In this method, an aglycon, which may be a non-steroid or a steroid having a reactive functional group (eg -OH, -SH, -COOH, -NH2, -NHR1) such as cholesterol, is glycosylated , so that glycosylation is carried out in a single step. For example, the steryl pyranoside is converted by oxidation to the corresponding 7-ketosteryl di-O-acyl-pyranoside, which is selectively reduced to obtain 7-beta-hydroxysteryl 2,3-dideoxy-alpha-D-erythro- corresponding hex-2-enopyranoside. Steroidal and nonsteroidal glycosides have advantageous pharmacological properties. In particular, the cholesterol glycoside exhibits selective cell destruction activity on malignant cells, in vivo, and has no side effects on normal cells. The glycosides have useful pharmacological properties which are the same as those of their respective non-glycosylated aglicons. Properties can include stimulating activity and anti-inflammatory (immunosuppressive or immunoregulatory) activity. |
| priorityDate | 1991-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 451.