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filingDate 1992-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2000-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_846124c00c09d79d8b71c91149f61409
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publicationDate 2000-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0596959-B1
titleOfInvention Self-adjuvanting peptide vaccine delivery system and production thereof
abstract PCT No. PCT/AU92/00377 Sec. 371 Date May 3, 1994 Sec. 102(e) Date May 3, 1994 PCT Filed Jul. 24, 1992 PCT Pub. No. WO93/02706 PCT Pub. Date Feb. 18, 1993The present invention provides self-adjuvanting vaccines for use in raising antibodies to peptides without the use of oil or alum adjuvants. Further, the present invention provides methods of therapy using these vaccines and has particular application in chemical castration. In one aspect the vaccine comprises in admixture a peptide conjugated to 1-3 fatty acids and a peptide conjugated to a carrier protein. In preferred forms the peptide is conjugated to the fatty acids via a tromethamine or ethanolamine derivative. The preferred protein carrier is Type 4 fimbriae.
priorityDate 1991-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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