| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e727909d17fde1129839931dba355e7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-475 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 |
| filingDate |
1991-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c633ce73f16d43bb13a0c6604960baf |
| publicationDate |
1995-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0592446-B1 |
| titleOfInvention |
Loading technique for preparing drug containing liposomes |
| abstract |
A process for loading of cationic, anionic or ionizable drugs through lipid bilayer membranes in the absence of a pH gradient comprises the formation of liposomes in an aqueous medium containing a combination of either the salt of an anion with high membrane permeability and a cation with low membrane permeability if the compound to be entrapped is an anionic drug or has an anionic potential; or the salt of a cation with high membrane permeability and an anion with low membrane permeability if the compound to be entrapped is a cationic drug or has a cationic potential. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9717723-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8992970-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8703181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9724303-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9730891-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10993914-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11052079-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8329213-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8147867-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9782349-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10722508-B2 |
| priorityDate |
1991-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |