http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0589665-A3

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28a869d6fc950d50f6df03f549ca3afa
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
filingDate 1993-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_743003f38fb5456a6ecc41c3fd671449
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2468f17edbe065dac7b3f63a1b58983d
publicationDate 1994-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0589665-A3
titleOfInvention 4,5,6,7-tetrahydro-1h-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine ii antagonistes
abstract A compound of formula (I): <CHEM> or a pharmaceutically acceptable salt thereof; wherein R<1> represents hydrogen, halogen, C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, R<2><0>(CH2)n- wherein R<2><0> represents C3-C8 cycloalkyl, naphthyl, phenyl, or phenyl substituted with one to five of C1-C4 alkyl, halogen atom, trifluoromethyl, hydroxy, C1-C4 alkoxy, C1-C3 acyloxy, amino, N-mono-C1-C4 alkylamino, N-di-C1-C4 alkylamino, C1-C4 thioalkyl, C1-C3 alkylsulfonyl, nitro, and -NHCOR<2><1> wherein R<2><1> represents C1-C3 alkyl, phenyl, C1-C3 alkylphenyl, aminophenyl, or C1-C4 alkylaminophenyl, and n is an integer of 1 to 6, R<2><0>-C(O)- wherein R<2><0> is as defined above, or R<2><0>-CH(OH)- wherein R<2><0> is as defined above; R<2> represents carbamoyl, mono- or di-C1-C6 alkylcarbamoyl, or 4- to 6-membered heterocyclic carbamoyl; R represents amino, carboxy, (1H-tetrazol-5-yl)phenyl, carboxyphenyl, carboxybenzamido, (1H-tetrazol-5-yl)benzamido, carboxyphenylcarbamoyl, or (1H-tetrazol-5-yl)-phenylcarbamoyl; R<3> represents -CH2(phenyl), -CH(phenyl)2, -CH(phenyl)CH3, -CH(phenyl) (cyclohexyl), -CH2CH2(phenyl), -CH2(C1-C6 alkoxyphenyl), or -CH2(hydroxyphenyl); and R<4>, R<7>, and R<8> each independently represents hydrogen or C1-C6 alkyl, is an angiotensin II antagonist.
priorityDate 1992-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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