http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0586378-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab6453f821a1a0b0f7142f1c084fb0a2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
| filingDate | 1991-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0152a6af44425d74335c49294b3c1e93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcd4a0299481692efee872b9ea23d240 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_514188f03604c51ef35431dde27d6621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f90acc48cb7cea0ffe6126bef69360 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33304ab0657e247a0ec8c8901749ed1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f408e1e00caed083b092a5361fbece3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_121185d4519e5f272c730a41df54889b |
| publicationDate | 1998-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0586378-B1 |
| titleOfInvention | Novel platinum(ii) complex and processes for preparing the same |
| abstract | Disclosed herein are novel platinum(II) complexes having a potent anti-tumor activity which are represented by the formula (1), <IMAGE> (1) <IMAGE> (a) <IMAGE> (b) wherein R1 and R2, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cycloalkane group together with the carbon atom attached thereto; two Xs jointly form a group represented by formula (a) or (b) wherein, R3 is a hydrogen atom or a methyl group; R4 and R5, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cyclobutane together with the carbon thereto; and the absolute configurations at the respective chiral centers in the 4,5-bis(aminomethyl)-1,3-dioxolane moiety are (4R,5R) or (4S,5S); processes for the preparing the same; and their use for treating animal or human cancer. Further, disclosed herein are novel intermediates useful for the preparation of the platinum(II) complexes and processes for preparing said intermediates. |
| priorityDate | 1991-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.