http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0580761-A4

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filingDate 1992-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab206affaeb5e4f97823a08dafb2eab1
publicationDate 1995-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0580761-A4
titleOfInvention Method and apparatus for immobilized enzyme reactions
abstract Perfusive matrices (10) useful in immobilized enzyme reactors (IMERs) are disclosed. The matrices define first and second interconnected sets of pores and an intraparticle high surface area (18) capable of immobilizing enzymes, in fluid communication with the second set of pores. The first and second sets of pores are embodied, for example, as the interstices (12) among particles and throughpores (14) within the particles. The particles also contain diffusive transport pores (16). The dimensions of the first and second sets of pores are such that, at fluid flow rates and pressure drops practical for immobilized enzyme reactions, convective flow occurs in both pore sets, and the convective flow rate exceeds the rate of diffusion of the substrate and product to and from immobilized enzymes within the particles. This approach allows rapid enzyme loading and substrate conversion reactions at optimal catalytic flow rates.
priorityDate 1991-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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