abstract |
Prepn. of water-soluble micronised substances, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation, comprises: (a) reducing, if necessary, the residual water from the micronised substance (MS) by drying opt. at an elevated temp. and/or vacuum; (b) conditioning with a solvent; and (c) eliminating residual solvent by storing in a dry place like vacuum or by purging with an inert gas. |