| abstract |
New ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities with intestinal selectivity, and corresponding to the general formula (I), in which R1 represents hydrogen or halogen; R2 represents halogen, hydroxy, protected hydroxy, aryloxy, lower alkoxy, lower haloalkoxy, nitro, cyano, amino or acylamino; R3 represents hydrogen or halogen; R4 represents hydrogen or lower alkyl; R5 represents hydrogen or lower alkyl; R6 represents hydrogen, hydroxy or lower alkyl; R7 represents hydrogen or lower alkyl; R8 represents hydrogen or halogen; R9 represents carboxy or esterified carboxy; and A represents lower alkylene; provided that R4 represents lower alkyl; that R5 represents lower alkyl; that R6 represents hydroxy or lower alkyl; or that R8 represents halogen when R1 represents hydrogen, that R2 represents halogen and that R3 represents hydrogen; their pharmaceutically acceptable salts; their preparation processes; and pharmaceutical composition containing them. |