| abstract |
New peptide derivatives of general formula (I): X1 X2 X3 Ile X5 X6, in which X1 represents a hydrogen, a residue of histidine, acetyl-histidine, or of D-histidine, X2 represents a residue of alanine, leucine, tryptophan, phenylalanine as well as their D series counterparts, X3 represents an alanine residue, as well as its D series counterpart, X5 represents an isoleucine, alanine, valine, norleucine residue, of leucine and aspartic acid as well as their D-series counterparts, X6 represents a residue of tryptophan, leucine, isoleucine, norleucine and their D-series counterparts, process for preparation and application as medicaments. |