http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0579769-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65515 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 |
| filingDate | 1992-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e66ca16e35ee6edc638a465261bd69e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba884192236706ff4c70a5194acc36e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22cbce8c477f3d5802189fcb11ba68d1 |
| publicationDate | 1998-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0579769-B1 |
| titleOfInvention | 2- and 5-alkyl and phenyl substituted 4-(1-hydroxy, 1-acyloxy or 1-carbamoyloxy)-5-hydroxy-2(5h)-furanones as anti-inflammatory agents |
| abstract | Novel anti-inflammatory furanone compounds have the following formula <IMAGE> where R1 independently is H, phenyl, C1-C6 alkyl substituted phenyl, halogen substituted phenyl, or alkyl of 1 to 6 carbons and n is an integer having the values of 1 or 2, and where when n is 1 the R1 group is attached either to the 3 or to the 5 position of the 2-furanone, when n is 2 then R1 is attached to both the 3 and 5 positions, with the proviso that when n is 1 then R1 is not H; Y1 is H, alkyl of 1 to 20 carbons, phenyl C1-C20 alkyl, C1-C20 alkenyl containing one or more olephinic bonds, PO(OH)2, PO(OH)OR2, PO(OH)R2, PO(OR2)2, where R2 is independently alkyl of 1 to 20 carbons, phenyl, or halogen substituted phenyl or C1-C6 alkyl substituted phenyl, further Y1 is CO-R3, CO-OR3, CONHR3, SO2R3, SO2NHR3, (CH2)p -O-R3, or (CH2)p-O-(CH2)m-O-R3, where p, and m, are integers and are independently 1 to 20 and R3 is H, C1-C20 alkyl, C1-C20 alkenyl containing one or more olephinic bonds, phenyl, halogen substituted phenyl or C1-C6 alkyl substituted phenyl, with the proviso that when Y1 is CO-R3, CO-OR3, and CONHR3 then R3 is not hydrogen; Y2 is H, an alkyl group of 1 to 25 carbons, phenyl, naphthyl, phenyl (C1-C20)alkyl-, naphthyl (C1-C20)alkyl-, halogen substituted phenyl, C1-C6 alkyl substituted phenyl, halogen substituted naphthyl, C1-C6 substituted naphthyl; Y3 is H, alkyl of 1 to 20 carbons, CO-R4, CO-O-R4, CO-NH-R4, PO(OR4)2 or PO(OR4)R4, where R4 independently is H, alkyl of 1 to 20 carbons, phenyl, or halogen substituted phenyl or C1-C6 alkyl substituted phenyl. |
| priorityDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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