http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0579769-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65515 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 |
filingDate | 1992-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba884192236706ff4c70a5194acc36e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e66ca16e35ee6edc638a465261bd69e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22cbce8c477f3d5802189fcb11ba68d1 |
publicationDate | 1994-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0579769-A1 |
titleOfInvention | 2- and 5-alkyl and phenyl substituted 4-(1-hydroxy, 1-acyloxy or 1-carbamoyloxy)-5-hydroxy-2(5h)-furanones as anti-inflammatory agents |
abstract | New furanone-based anti-inflammatory compounds have the formula (1) in which R1 independently represents H, phenyl, C1-C6 substituted phenyl alkyl, halogen substituted phenyl, or alkyl having 1 to 6 carbon atoms, and n represents an integer equal to 1 or 2, and when n is equal to 1 then the group R1 is attached either in position 3 or in position 5 of 2-furanone, and when n is equal to 2 then R1 is attached to 2 positions 3 and 5, provided that when n equals 1 then R1 is not H; Y1 represents H, alkyl having from 1 to 20 carbon atoms, phenyl C1-C20 alkyl, C1-C20 alkenyl containing one or more olefinic bonds, PO (OH) 2, PO (OH) OR2, PO (OH) R2, PO (OR2) 2, where R2 independently represents alkyl with 1 to 20 carbon atoms, phenyl, or halogen substituted phenyl or C1-C6 substituted phenyl alkyl, and Y1 represents CO-R3, CO-OR3, CONHR3, SO2R3, SO2NHR3 , (CH2) pO-R3, or (CH2) pO- (CH2) mO-R3, where p, and m are whole numbers and independently represent numbers between 1 and 20 and R3 represents H, C1-C20 alkyl, C1-C20 alkenyl containing one or more olefinic, phenyl, halogen substituted phenyl or C1-C6 alkyl substituted phenyl, provided that when Y1 represents CO-R3, CO-OR3, and CONHR3 then R3 is not hydrogen; Y2 represents H, an alkyl group having from 1 to 25 carbon atoms, phenyl, naphthyl, phenyl (C1-C20) alkyl-, naphthyl (C1-C20) alkyl-, halogen substituted phenyl, C1-C6 substituted phenyl alkyl , halogen substituted naphthyl, C1-C6 substituted naphthyl; Y3 represents H, alkyl having 1 to 20 carbon atoms, CO-R4, CO-O-R4, CO-NH-R4, PO (OR4) 2 or PO (OR4) R4, where R4 independently represents H, alkyl having from 1 to 20 carbon atoms, phenyl or halogen substituted phenyl or C1-C6 alkyl substituted phenyl. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013021105-A2 |
priorityDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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