abstract |
Disclosed are new alkylenediamine derivatives of the following formula which are effective for treatment of dysuria are disclosed:n n wherein R¹ is hydrogen, alkyl, or a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group; R² is a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group; R³ and R⁴ represent hydrogen, alkyl, aralkyl or aryl; or R³ and R⁴ are combined to form one of substituted or unsubstituted 5- to 7-membered heterocyclic groups; X is oxygen, sulfur or imino; Y is oxygen or sulfur; Z is -CH₂-, -CO- or -CS-; m is an integer of 0-4; n is an integer of 0-4; r is 0 or 1; and p and q represent an integer of 0-5 provided that p plus q is 1-5. |