| abstract |
Azole derivatives are represented by formula (I):n n wherein R₁ and R₂ each are H or C₁-C₄ alkyl; R₃ is H, OH, H, halogen, haloalkyl, C₁-C₄ alkyl or phenyl, and if there are two or more R₃ groups, such R₃ groups may be the same or different; n is an integer from 0 to 5; Y is N or CH; and X is O, S or NH. The azole derivatives, stereoisomers thereof, and pharmaceutically acceptable salts thereof have antimycotic and aromatase inhibitory activities. This invention also discloses compositions containing them, and a method of treating mycosis and estrogen-dependent diseases. |