| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e29526f284c0155fd79806c9dd5a1c7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2090-306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6417
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-00061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2090-3941 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-8507
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B10-0233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B19-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate |
1993-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5965948e34e7ee30f1f79eeaadb022c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d81bbe19ba728827ad4911349676bff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c41442d2897304836a41d08cd66bd903 |
| publicationDate |
1993-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0573264-A2 |
| titleOfInvention |
Apparatus and method of use for a photosensitizer enhanced fluorescence based biopsy needle |
| abstract |
A method and apparatus is disclosed for the instant intraoperative detection and biopsy of metastatic cancer using fluorescence spectroscopy. A photosensitizing agent selectively retained by cancerous tissue is administered prior to surgery. A fiberoptic probe (1) integrated with a biopsy device (2) illuminates the examined tissue and causes fluorescence which is recorded by a spectrograph and plotted as a spectral curve. The intensity ratio (S1/S2) for the fluorescence from the photosensitizing agent (S1) and autofluorescence (S2) for the examined tissue is compared with the intensity ratio at the same wavelengths for primary tumor and normal tissue. Tissue that displays an intensity ratio different from that of normal tissue can immediately be analyzed for the depth of tumor involvement and then excised for histological examination using the biopsy device. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9801074-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0174251-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0174252-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110710953-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6296608-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112082942-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8135454-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0174251-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102253019-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0174252-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19854291-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19854291-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10143450-B2 |
| priorityDate |
1992-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |