Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1991-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1999-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a96b1afd85bae8c17d3914925dddf2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8a57ba1f893b761ef5b47bf8452bf20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28e255497dd1297b939ea2fa49083fc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1620e376631d7f84843af1ec9b09f46b |
publicationDate |
1999-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0567645-B1 |
titleOfInvention |
Dna which codes for neurotrophic activity inhibitor and use thereof |
abstract |
A DNA which codes for a novel protein GIF which inhibits neurotrophic activity and which is present in the brain of a healthy man but is not in the brain of a patient with Alzheimer's disease has been cloned from a human cerebral cDNA library and a human genome DNA library. Escherichia coli has been transformed by a vector containing the cDNA integrated thereinto to express the GIF. The DNA which codes for a cloned GIF can be used in the genetic diagnosis and treatment of Alzheimer's disease and a large amount of the GIF can be produced by expressing said DNA in a transformant. <IMAGE> |
priorityDate |
1990-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |