abstract |
This invention is based on the observation that the administration to a mamal of a selective 5-HT 1A agonist, e.g. 8-OH-DPAT or (±)-4-(di-n-propyl)amino-6-methoxy-1,3,4,5-tetrahydrobenz[c,d]indole, or a pharmaceutically acceptable salt thereof, induces hippocampal theta rhythm associated with primary (i.e. short-term) memory, and learning functions. |