abstract |
This invention provides a tissue closure agent supplemented with a growth factor and methods of using the tissue closure agent to accelerate healing, endothelialization of vascular prostheses, and in vitro proliferation and differentiation of animal cells. This invention provides in particular a fibrin glue which is supplemented with at least one growth factor such as a growth factor binding to heparin and / or bone morphogenic proteins. The growth factor or factors are selected based on the intended use. |