http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0562185-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08 |
| filingDate | 1992-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aacddb33f75d425c0a3ca856dd63203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3970f18332f623d3a16f4fd6d4debb44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f99be0971e390387c4e0fbef24a5e04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acdfdf1440f299d1e7b41c78ed9ddfd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26f4fe496875746d3913522aa8950a89 |
| publicationDate | 1993-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0562185-A1 |
| titleOfInvention | 3-(Arylmethyl)-1-(3'-diethylaminopropyl) pyrrolidines and process of preparation thereof |
| abstract | The novel compounds 3-(arylmethyl)-1-(3'-diethylaminopropyl) pyrrolidines are disclosed which have the general formula:n n wherein R represents an alkoxy group having 1 to 6 carbon atoms, like methoxy, ethoxy, propoxy or butoxy and a process for preparing the same. Particularly, the invention provides the compound having the above said formula wherein the alkoxy substituent is in the 4 position of the benzene ring or the substituent methylenedioxy at 3 and 4 position. The compounds have the property of reversing the resistance of chloroquine resistant strains of the malarial parasite P. berghi in vivo and P. falciparum in vitro and can be used for reversing the resistance of human malarial parasites, particularly P. falciparum . The invention also includes compositions containing the new compounds and an anti-malarial drug, preferably chloroquine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9524390-A1 |
| priorityDate | 1992-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.