| abstract |
A catalyst for asymmetric induction is provided which comprises a titanium (IV) alkoxide and an amino acid amide derivative of formula (I):n n wherein R¹ is isopropyl, isobutyl, sec-butyl, tert-butyl, phenyl or benzyl, R² and R³ are the same or different and each is lower alkyl, C₃ to C₈ cycloalkyl, unsubstituted or substituted phenyl or hydrogen or R² and R³ together form a divalent C₃ to C₇ alkylene group optionally containing one or more hetero atoms, R⁴ is chlorine, bromine, iodine, lower alkyl or unsubstituted or substituted phenyl, R⁵, R⁶ and R⁷ are the same or different and each is hydrogen, halogen, methyl or methoxy or R⁵ is as defined above and R⁶ and R⁷ together form -CH=CH-CH=CH- or -OCH₂O- or R⁷ is as defined above and R⁵ and R⁶ together form -CH=CH-CH=CH- or -OCH₂O- and * denotes an absolute configuration of S or R. |