http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0558621-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b919a09598a02c07e8429b1441b76e1
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-43
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-43
filingDate 1991-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40519434652a61245b14be859200b819
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08946b387adce814224800a69900c3b6
publicationDate 1993-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0558621-A1
titleOfInvention PROCESS FOR IMPROVING THE FLOW CHARACTERISTICS OF CRYSTALLINE IBUPROFENE.
abstract A process for producing crystalline ibuprofen having a crystal shape which is characterized by a particle length greater than 75 microns on average and a geometric length to width ratio exceeding about 4:1 and up to about 5:1. The process involves crystallizing ibuprofen from a saturated solution of ibuprofen in a liquid hydrocarbon solvent by seeding and cooling such solution to a temperature between approximately 0°C and about -20°C at a rate intended to retard the formation of primary seed crystals and promote the formation of secondary seed crystals. Crystalline ibuprofen is separated from the sludge produced by such cooling.
priorityDate 1990-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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