abstract |
The invention relates to compounds of the formula I, <IMAGE> in which either R1 is a radical of the formula Ia, - (CH2) nO-NH2 (Ia) in which n is 0 or 1, and R2 is hydrogen, or R1 is hydrogen and R2 is a radical of the formula Ib, - (CH2) pO-NH2 (Ib) in which p is 1 or 2; and wherein R is C1-C2-alkyl which is bonded to a carbon atom of the central piperidine ring system but not to the same carbon atom as R1 of the formula Ia or as R2 of the formula Ib; where m is 1 or 2, and salts thereof, processes for the preparation of these compounds, intermediates obtained in the preparation, pharmaceutical preparations containing these compounds, and the use of these compounds for the therapeutic treatment of the human or animal body and for the preparation of pharmaceutical preparations. The compounds of formula I are ornithine decarboxylase inhibitors. |