abstract |
The present invention relates to the field of immunology, and more particularly to the field of antibodies and the production of antibodies. More specifically, the present invention relates to bispecific antibodies, to the hybridomas that produce them, to the father hybridomas, to the production and selection of hybridomas and hybridomas, as well as to the purification of bispecific antibodies. . Specific examples of bispecific monoclonal antibodies are presented which recognize both the human multidrug resistance antigen, P-glycoprotein and the human FCgamma receptor III (hFcgammaRIII). These bispecific antibodies are useful for killing cancer cells. |