| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df53cdf55050f3f4580e1931741875b7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate |
1993-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d6a3137546a6b223de8b0f7d4ad170
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16fbedd93e1826c87d39daf15ecc6861
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71af899fbde3640cdc8d16662042efce |
| publicationDate |
1998-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0556768-B1 |
| titleOfInvention |
Process for the production of ceftriaxone |
| abstract |
The invention relates to a new process for the production of the disodium salt hemiheptahydrate of ceftriaxone by reacting 7-amino-3-{[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)t hio]methyl}-3-cephem-4-carboxylic acid with 2-(2-aminothiazol-4-yl)-2-syn-methoximinoacetic acid-(2-benzthiazolyl)thiolester in the presence of a base, characterized in that the reaction and the crystallization of the disodium salt hemiheptahydrate of ceftriaxone are carried out in aqueous acetone. |
| priorityDate |
1992-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |