http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0554385-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6115b7f4561db088f26a575e9339fed0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01049 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate | 1991-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f522c3244a1a872f05bb10c00185abd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f992b78fe71791224f34bcde9334ca69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737d038eae5dbc5938dc05db8244e5a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c67de3a06a96c896d0b8b31029352b17 |
| publicationDate | 1993-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0554385-A1 |
| titleOfInvention | Cloning and expression of biologically active alpha-n-acetylgalactosaminidase |
| abstract | The present invention relates to the production of human alpha-GalNAc by cloning and expression of the alpha-GalNAc coding sequence in eukaryotic host cell expression systems. These eukaryotic expression systems, and in particular the mammalian host cell expression systems described here, allow the realization of the appropriate co-translational and post-translational modifications necessary for correct maturation, for example, glycosylation, phosphorylation, etc. , and sorting the expression product so that an active enzyme is produced. The alpha-Ga1NAc produced according to the invention can be used in the treatment of Schindler's disease or for the hydrolysis of alpha-N-acetylgalactosaminyl fractions in various glycoconjugates. |
| priorityDate | 1990-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1764.