| abstract |
Uracil reductase inactivators, in particular a 5-substituted uracil or a 5,6-dihydro-5-substituted uracil, potentially 5-fluorouracil and finding their use particularly in the treatment of cancer. The 5-substituent is selected from bromo, iodo, cyano, C1-4 halo-substituted alkyl, C2-6 alkenyl, 1-halo C2-6 alkenyl, C2-6 alkynyl and C2-6 halo-substituted alkynyl. |