| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a217ee61cc2de987e8764b98998383b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7455 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 |
| filingDate |
1991-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbf9b79647ed8a3a557db3255902f542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1c4e27a9742751e869d92d64f37ba4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58c67d721de5c1fe3646a9d7ca0f57c8 |
| publicationDate |
2002-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0544826-B1 |
| titleOfInvention |
Superior thrombomodulin analogs for pharmaceutical use |
| abstract |
The present invention relates to the use of analogs of thrombomodulin ("TM") that have the ability to enhance the thrombin-mediated activation of protein C but which have a significantly reduced ability to inhibit the direct procoagulant activities of thrombin, such as, for example, thrombin-mediated conversion of fibrinogen to fibrin. These analogs are useful in, for example, antithrombotic therapy. Novel proteins, nucleic acid gene sequences, pharmaceuticals and methods of inhibiting thrombotic activity are disclosed. Included are methods for increasing the circulating half life of the proteins. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011157283-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2120049-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010142461-A2 |
| priorityDate |
1990-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |