abstract |
A renin inhibitor compound of the formula (I), wherein X represents O, NH or S and G represent a mime of the Leu-Val cleavage site of angiotensinogen; or a salt, a pharmaceutically acceptable ester or prodrug of said compound; provided that the compound is not N- (3- (4-morpholino) propyl) -5 (S) - (2 (S) - (1 (S) - (4-methoxymethoxy) piperidine-1-yl) carbonyl -2-phenyl) ethoxyhexanamido) -6-cyclohexyl-4 (S) -hydroxy-2 (S) -isopropylhexanamide. |