Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f3395f9de7da2db784d903372d5760e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-09 |
filingDate |
1991-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eb29af26b075d6acf81893462934c70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec91862864b392e80c3faf6b9abc116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2861d80f0e39a0208ff24d21c0556a7a |
publicationDate |
1993-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0543913-A1 |
titleOfInvention |
Oligo(alpha-arabinofuranosyl nucleotides) and alpha-arabinofuranosyl precursors thereof |
abstract |
New oligonucleotides formed from alpha-D-arabinofuranosyl nucleosides monomers, including oligonucleotides in which one or more of the monomer units are functionalized. The invention also relates to functionalized monomeric alpha-D-arabinofuranosyl nucleosides and nucleotides. A general formula for oligomers is (Ib) in which B is a nucleotide base which varies from one monomer unit to the next in a preselected oligonucleotide sequence; R is phosphate, phosphorothioate, phosphoramidate or alkanephosphonate; t is 1 for functionalized monomer units and zero for the others; W is a chemical bonding arm; A is a functional group; and n is the number of monomer units in the oligomer. The oligomers are useful in diagnostic and chemotherapeutic applications. A new reaction is also described in which an alpha-D-arabinofuranosyl nucleoside with exposed hydroxyls at positions 2 'and 3' is selectively protected at position 2 'in a single reaction. |
priorityDate |
1990-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |