| abstract |
Compounds of structure (I) in which R represents C1-8 alkyl (phenyl) p, C2-8 alkenyl (phenyl) p, C2-8 alkynyl (phenyl) p, C3-8 cycloalkyl or C1-8 alkyl C3-8 cycloalkyl, p is 0 to 2; n is 0 to 6; A represents a bond, oxygen, sulfur or NR1; R1 represents hydrogen, C1-8 alkyl or phenyl C1-4 alkyl; m is 0 to 3; and Ar is aryl or heteroaryl, each of which may be optionally substituted, as well as their salts; processes for the preparation of said compounds (I), pharmaceutical compositions containing them and their use in medicine, particularly as calcium blocking agents. |