http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0542099-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-32 |
| filingDate | 1992-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9841b80d1b4b41d06f9a1569b1bcba65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeac174a21f07e89f997e5bc30b7b83b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51a49cf3b6a598f5c00c0bf3962a10d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd09be018a19566b3a7f9d6aab66a734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a5aeca843504dd9931d0fcc5b370da2 |
| publicationDate | 1998-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0542099-B1 |
| titleOfInvention | Process for preparation of optically active 1,3-imidazolidin-4-ones |
| abstract | 2.1. The said compounds are to be prepared as economically and cleanly as possible. Depending on the costs of the starting compounds, an optimisation should be possible with respect to the necessary process steps, the yield and/or the purity. Complicated process steps such as extractions and problematical solvents such as dichloromethane should particularly be dispensed with. 2.2. The 1,3-imidazolidin-4-ones of the general formula <IMAGE> are obtained pure in their preparation, in particular by precipitation, it being possible to employ an optically active acid to 0.5 - 0.8 eq for resolving the racemate. The undesired enantiomer can be racemised in an inert solvent, and the cyclisation to the imidazolidinone can even be carried out by means of the optically active acid, after which the resolution of the racemates takes place directly. 2.3. The 1,3-imidazolidin-4-ones are useful starting materials for the preparation of branched or unbranched, proteinogenic or non-proteinogenic alpha -aminoacids by means of diastereoselective alkylation and subsequent ring cleavage. |
| priorityDate | 1991-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.