http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0541663-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94e944e408d7c0eeacfb9df107df5d2f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59 |
filingDate | 1991-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3de845ac9ab7c7f7a46288b66c9acb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ef4af5d00aef120d9a2b32e4298b0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba848eb93c7d8aa22fab0ccf84bf8257 |
publicationDate | 1993-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0541663-A1 |
titleOfInvention | Peptides and pharmaceutical compositions having glycoprotein hormone agonistic or antagonistic activity |
abstract | Peptide exhibiting (ant) agonist activity of glycoprotein hormones and comprising at least two partial peptides selected from: (1) a partial peptide having an amino acid sequence comprising TDSDS based on amino acids (92, 88, 89, 90 and 91) of the beta chain of the glycoprotein hormone hFSH, or else a corresponding sequence of another glycoprotein hormone and / or of another animal species; (2) a partial peptide having an amino acid sequence included in the alpha chain of glycoprotein hormones and comprising SRAY; (3) a partial peptide having an amino acid sequence comprising TRDL based on amino acids (34-37) of the beta chain of the glycoprotein hormone hFSH, or else a corresponding sequence of another glycoprotein hormone and / or of another animal species; and (4) a partial peptide having an amino acid sequence comprising AHASTA, derived from amino acids (82-87) of the alpha chain of human glycoprotein hormones by replacing cysteines with alanines, or a corresponding sequence of a glycoprotein hormone from another animal species; said partial peptides being capable of being linked to one another by bridging groups. Variants and derivatives with agonist or antagonist activity of glycoprotein hormones have also been provided. |
priorityDate | 1990-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 234.