| abstract |
The present invention is directed to a compound of the formula (I)n n wherein n R represents a hydrogen atom or an acyl, aroyl or cycloalkylcarbonyl radical or a residue of formulan n R₁ represents an alkyl radical; n R₂ represents an aryl or heteroaryl radical, or R₁ represents an alkylene chain attached to a carbon atom in an ortho position of the R₂ aryl or heteroaryl radical relative to a carbon of the R₂ aryl or heteroaryl radical linked to the propanoyl moiety; n R₃ represents a hydrogen atom or an alkyl, aryl, alkoxy or aryloxy radical; and n R' represents a hydrogen atom or an alkyl, aralkyl, acyl or aroyl radical; n and the pharmaceutically acceptable salts thereof. n The invention is also directed to the preparation of these compounds, pharmaceutical compositions comprising the compounds and methods for their pharmaceutical use. |