http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0538332-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 |
| filingDate | 1991-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1997-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cabc765bf3c49b959b63d0a7d996af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13423130ce956a3ad12ae077b933281a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93635decfd4e628ef854d34a0c08a8a9 |
| publicationDate | 1997-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0538332-B1 |
| titleOfInvention | Polycyclic guanine derivatives |
| abstract | PCT No. PCT/US91/04154 Sec. 371 Date Dec. 14, 1992 Sec. 102(e) Date Dec. 14, 1992 PCT Filed Jun. 20, 1991 PCT Pub. No. WO91/19717 PCT Pub. Date Dec. 26, 1991.Novel polycylic guanine derivatives of the formula: <IMAGE> (I) and <IMAGE> (I') wherein J is oxygen or sulfur, R1 is hydrogen, alkyl or alkyl substituted with aryl or hydroxy; R2 is hydrogen, aryl, heteroaryl, cycloalkyl, alkyl or alkyl substituted with aryl, heteroaryl, hydroxy, alkoxy, amino, monoalkyl amino or dialkylamino, or -(CH2)mTCOR20 wherein m is an integer from 1 to 6, T is oxygen or -NH- and R20 is hydrogen, aryl, heteroaryl, alkyl or alkyl substituted with aryl or heteroaryl; R3 is hydrogen, halo, trifluoromethyl, alkoxy, alkylthio, alkyl, cycloalkyl, aryl, aminosulfonyl, amino, monoalkylamino, dialkylamino, hydroxyalkylamino, aminoalkylamino, carboxy, alkoxycarbonyl or aminocarbonyl or alkyl substituted with awl, hydroxy, alkoxy, amino, monoalkylamino or dialkylamino; Ra, Rb, Rc, and Rd are defined in the specification; and n is zero or one. The compounds of formulas (I) and (I') are useful as antihypertensive, muscle relaxant and bronchodilating agents. |
| priorityDate | 1990-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 986.