| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed28726de9f916f355f8adc331e736b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-166 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
| filingDate |
1991-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e91f6ea21e6e47650eb50ddbe26b32f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faab9ceb8cc7fe696927b4d97009c21b |
| publicationDate |
1993-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0535154-A1 |
| titleOfInvention |
Heterohybridomas producing human monoclonal antibodies to hiv-1 |
| abstract |
Heterohybridomas producing human monoclonal antibodies against an HIV-1 neutralizing epitope are prepared by transformation of peripheral blood lymphocytes using the Epstein-Barr virus, by selection of cells producing an antibody against a synthetic peptide representing a portion of the neutralizing epitope, and by fusion of this with a heteromeloma cell. The invention also relates to a method for producing a human monoclonal antibody specific for an HIV-1 neutralization epitope from the heterohybridoma, as well as human monoclonal antibodies specific for specific peptide epitopes of the V3 loop of the HIV glycoprotein Gp120. |
| priorityDate |
1990-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |