http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0535148-A4
Outgoing Links
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|---|---|
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| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0669 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-50 |
| filingDate | 1991-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1994-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0535148-A4 |
| abstract | Basic fibroblast growth factor (bFGF) is used in vitro to stimulate production of large numbers of bone marrow stromal cells which are useful as feeder cells for generating hemopoietic progenitor cells in cultured bone marrow. Basic FGF is also used directly in whole bone marrow culture to increase the numbers of hemopoietic progenitor cells. Bone marrow cells cultured under the influence of bFGF are used for autologous or allogeneic bone marrow transplantation. To accelerate the rate of bone marrow engraftment bFGF is administered together with one or more colony stimulating factors to a bone marrow transplant recipient. Alternatively, or additionally, bFGF is administered to a bone marrow donor to increase the concentration of hemopoietic progenitor cells present in the donated bone marrow. Basic FGF is also administered to subjects with aplastic conditions in order to stimulate endogenous cytokines such as colony stimulating factors and interleukins. |
| priorityDate | 1990-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 585.