http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0533378-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-20 |
| filingDate | 1992-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e031417b098d58fed6ad2206f0528fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c44f4053aff43c2315419c3a1617796 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7300f520bdf663a3be77a40dd77f2750 |
| publicationDate | 1993-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0533378-A1 |
| titleOfInvention | Process for producing octahydrocoumarin or derivative thereof |
| abstract | For producing octahydrocoumarin or a derivative thereof represented by:n n wherein R₁ to R₄ each represents hydrogen or C1-5 alkyl (a) a 3-(2-oxocyclohexyl)propionic acid ester or derivative thereof represented by:n n where R₁ to R₄ are as defined above and R₅ represents C1-5 alkyl, is reduced at 0-25°C using hydrogen in the presence of a catalyst (e.g. Ru, Rh, Pd, Ph) and optionally a solvent and/or an acid or alkali, thereby to convert the compound of formula (1) to a 3-(2-hydroxycyclohexyl)propionic acid ester or derivative thereof represented by:n n wherein R₁ to R₅ are as above and optionally removing e.g. by distillation the alcohol formed; (b) the compound of formula (2) is cyclized at 0-300°C preferably with an acid or alkali as catalyst and with continuous removal of reaction products or alcohol thereby to convert the compound of formula (2) to octahydrocoumarin or a derivative with elimination of an alcohol. n The product (3) is usually a mixture of cis - and trans - isomers and is obtained in good yield. It is useful in perfumes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5639893-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0757989-A1 |
| priorityDate | 1991-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.