Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate |
1992-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f5854ce9eafea408ff1e22cda21ca19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ddfe2ad4e94187735e26a00a20be36a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d7be11cddadde60aafbd29c87b9c2c |
publicationDate |
1993-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0531981-A1 |
titleOfInvention |
Process for the preparation of a cephalosporin antibiotic |
abstract |
The present invention provides an anhydrous acylation process for the preparation of antibiotic, cefepime dihydrochloride hydrate which is substantially free of the anti-isomer and the A 2 isomer comprising the N-acylation of a silylated derivative of 7-amino-3-[(1-methyl-1-pyrrolidinio)-methyl]ceph-3-em-4-carboxylate with the syn-isomer of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetyl chloride hydrochloride. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0587121-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2218723-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004092183-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006008160-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7847093-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19980019860-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1762570-A1 |
priorityDate |
1991-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |