| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c6191997ed6dda6a5a3582e10b0b3dbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_975c4266f8a49abcf34dd5d54f8f5bd5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-815 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-815 |
| filingDate |
1992-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2df3c106ff7161001d6ba1a752c8f680
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_592872da13717c451d1a4f8c6984614b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a7f203c1a649be919c8a24da9495100
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a93f40e9e1a4ca4f6ba3bd8a956982cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c76eb28f8f9de0a411b80b13202531ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90dc15dd02189b314fb264170a6a961f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04285305483249c91b5b0675367f20de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4e380423f6be949f03e693920d8afd7 |
| publicationDate |
1996-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0531537-B1 |
| titleOfInvention |
Hirudin analogue or salt thereof, production thereof, and anticoagulant containing the same as active ingredient |
| abstract |
A hirudin analogue having high antithrombin activity and platelet aggregation resistance, represented by formula Phe-Glu-A-Ile-Pro-B-Tyr(R)-Tyr(R) and having a tyrosine residue with its hydroxyl group optionally sulfated. In the said formula, A represents Glu or Pro; B represents Glu, Tyr(R), Glu-Asp or Glu-Tyr(R); and (R) represents the hydroxyl group of a tyrosine residue or the sulfate thereof (-O-SO3H). A process for producing a hirudin analogue by sulfating the hydroxyl group of the tyrosine residue. An anticoagulant containing the hirudin analogue (I) as the active ingredient. |
| priorityDate |
1991-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |