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filingDate 1992-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45e3182b6dd6a3792ec6c9d8a2795d0
publicationDate 1993-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0529201-A2
titleOfInvention Chromatographic method with micellar on-column enrichment
abstract On-column enrichment is provided for a sample (105) having both polar and nonpolar analytes by mixing (302) the sample with surfactant in a polar solvent. The surfactant causes the nonpolar analytes to be incorporated in micelles that dissolve in the polar solvent. The concentration of surfactant is maintained at a level sufficient to maintain the micelles as the mixture is introduced (303) onto the head (204) of a chromatographic column (110). Once sample introduction is completed, the mixture is diluted (304) so that the surfactant concentration drops below that required to maintain the micelles, which thus break up. The analytes are then separated (305) using reverse-phase gradient elution.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004058378-A1
priorityDate 1991-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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