| abstract |
A novel thiazolidine-2,4-dione derivative with hypoglycemic and aldose reductase inhibitory activities, represented by the general formula (1) or (2), a salt thereof, a process for producing the same, and a medicine containing the same, wherein R<1> and R<2> may be the same or different from each other and each represents hydrogen or lower alkyl; R<3> represents phenyl naphthyl, benzoyl, 5- or 6- membered heterocycle or a benzene-containing condensed ring thereof, all of which may have at least one substituent; A represents carbonyl, sulfonyl or a free bond; and B represents lower alkylene, lower alkenylene or a free bond, in formula (2) R<4> represents hydrogen or lower alkyl, and R<1> and R<3> are as defined above. <CHEM> |