http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0516845-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7dfd84f9157ae12c41e319ec325338d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-53 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate | 1989-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f59e396ae10fe9e23b677d90daf74a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6a6647ee885d0f48590d2ce2631ec50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19f0d59e1542ec3a5d716bece5560454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bf1e72b2b86cbb67d5cd26a219fd891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b237d15751c08fbc091d1485ae0d05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fac82a3b6a74f2f8a9df61b825b14880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74b7ec523a1ea4c65d6cbc95620253e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5628d8fee831109fc0ac977d33b3acca |
| publicationDate | 1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0516845-B1 |
| titleOfInvention | Novel megakaryocytic colony stimulating factor and process for its preparation |
| abstract | According to this invention, a novel megakaryocytic colony stimulating factor is obtained by culturing a cell strain of human pulmonary large cell cancer, for example, PC-13 cell strain or human lung cancer cell strain MC-1 separated as monoclonal cells from PC-13 cell strain, recovering a supernatant of the culture liquor, collecting from the supernatant a megakaryocytic colony stimulating factor (Meg-CSF) comprising a protein having the activity of forming a megakaryocytic colony from myeloid cells when applied to human or mouse myeloid cells in vitro and the activity of increasing the number of platelets in the peripheral vessel in vivo, and purifying the factor. The obtained colony stimulating factor is a protein having a molecular weight of 24,000 and an isoelectric point of 4.5 to 5.5, and is useful for treating a certain kind of platelet reducing diseases. This factor can be mixed with conventional various excipients to form medicinal compositions in various preparation forms. |
| priorityDate | 1988-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 739.