http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0513400-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_991057d5fe05f6cb1aecedce789215ba |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60 |
| filingDate | 1991-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6cc3772e8fb7df792ffe57f906aa537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54aa8d47d6c84dbce5149a180647b72c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a32ce6f013613ecd60846271aade65c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de09003ed853a047e90ee7679b53acd3 |
| publicationDate | 1992-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0513400-A1 |
| titleOfInvention | Use of 2-ethoxy benzoic acid for the manufacture of a medicament as analgesic, antipyretic, and/or antiphlogistic |
| abstract | The present invention relates to a drug with analgesic, antipyretic and / or antiphlogistic action based on a Salicylsäurederivates. The state of the art is always looking for alternatives to drugs such as acetylsalicylic acid (ASA) and etheneamide, in order to eliminate incompatibilities or to be able to offer simpler and better substances which act as quickly as possible in a wide variety of application possibilities. Surprisingly, the invention has now been able to demonstrate that ethene-amide is rapidly and completely metabolized in the human body to 2-ethoxybenzoic acid. Ethenzamide is just a pro-drug. Metabolism to salicylamide could be excluded. The analgesic effect of 2-ethoxybenzoic acid could also be demonstrated. It correlates with serum levels and lasts longer than 8 hours. 2-ethoxybenzoic acid is absorbed very quickly. The serum maxima are reached after only 30 minutes; 2-ethoxybenzoic acid is still detectable in the serum after 24 hours. These properties make 2-ethoxybenzoic acid an ideal analgesic with a rapid onset of action that has no effect on blood clotting. Because of the higher bioavailability, the single doses can be reduced. Due to the physicochemical properties of 2-ethoxybenzoic acid, the use in the form of a solution is possible, so that in addition to solid dosage forms for oral and rectal use and liquid preparations such as dripping solutions or injection solutions can be prepared and used. |
| priorityDate | 1991-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.