abstract |
The present invention relates to a cephalosporin compound including the pharmaceutically acceptable non-toxic salts, physiologically hydrolyzable esters, hydrates and solvates thereof of the formula(I) and its isomers:n n wherein:n R¹ is a C₁₋₄ alkyl, C₃₋₄ alkenyl, C₃₋₄alkynyl or -C(R³)(R⁴)COOH wherein R³ and R⁴, which may be the same or different, are hydrogen, C₁₋₄ alkyl group, or constitute a C₃₋₇ cycloalkyl group with the carbon atoms to which R³ and R⁴ are attached; R², which may be attached to N a or N b , is a C₁₋₄ alkyl, C₃₋₄ alkenyl, C₃₋₇ cycloalkyl, aryl or amino group; and Q₁ and Q₂, which may be the same or different, are CH or N. |