| abstract |
A benzothiazole derivative or a pharmacologically acceptable salt thereof which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective. n A benzothiazole derivative represented by the following general formula (I):n n wherein R¹ and R³ are either same or different and each represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a group represented by the formula:n n (wherein p is an integer of from 1 to 4), or a group represented by the formula:n n (wherein R⁷ represents a lower alkyl group); n R⁴ represents a hydrogen atom, a lower alkyl group, a phenyl group, a group represented by the formula:n n (wherein q is an integer of from 1 to 4), or a group represented by the formula:n n (wherein R⁷ represents a lower alkyl group); n or R³ and R⁴ may form a benzene ring together with the carbon atoms to which they are bound; n R² represents a hydrogen atom or a protective group of a hydroxyl group; and n R⁵ and R⁶ are either same or different and each represents a hydrogen atom, a lower alkyl group, a group represented by the formula:n n (wherein r is an integer of from 1 to 4), or an acyl group; nor a pharmacologically acceptable salt thereof. |