| abstract |
Method of treatment and / or prophylaxis of nausea and bradycardia and / or hypotension associated with myocardial instability in mammals, for example in humans. This method provides for administering to mammals requiring this treatment and / or this prophylaxis an effective and / or prophylactic amount of a 5-HT3 receptor antagonist, for example a compound of formula (I): XAR, or a salt thereof. -this pharmaceutically acceptable, where X is a phenyl group or a 5- or 6-membered monocyclic heteroaryl group. In either case, each group is fused to a saturated carbocyclic or heterocyclic ring or 5-7 element unsaturated; A is a connecting part; and R is a saturated azabicyclic part or an imidazolyl part. |