| abstract |
The present invention relates to a composition for topical application for regulating wrinkles in mammalian skin comprising a safe and effective amount of a peptide having the amino acid sequence n n Q a - (Xaa) n Arg Ser Arg Lys (Xaa) n - Q c n n n wherein each n is independently an integer selected from the group consisting of 0, 1, 2 and 3, Xaa is independently any amino acid, each amino acid is protected or unprotected, Q a is selected from the group consisting of hydrogen and an amino-terminus blocking group, and Q c is selected from the group consisting of hydrogen and a carboxy-terminus blocking group; and a safe and effective amount of a pharmaceutically acceptable carrier. |