http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0503035-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4aa695c94bf363eae216eeaa69842e2e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C35-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-592 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C401-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-21 |
| filingDate | 1991-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05f203bb432ced037f8e8c4569d6f5b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c2faf034aea7cb2bb1ce315d879b3f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44ca52e78cd11f15c95f2862bf15ee7c |
| publicationDate | 1992-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0503035-A1 |
| titleOfInvention | NOVEL 1$g(a)-HYDROXY VITAMIN D 4? AND NOVEL INTERMEDIATES AND ANALOGUES |
| abstract | New 1alpha-hydroxy vitamin D4 and new analogs, 1.25 dihydroxy vitamin D4 and 1.24 dihydroxy vitamin D4 which are useful as active compounds of pharmaceutical composition for the treatment of disorders of calcium metabolism. The preparation of the new 1alpha-hydroxy vitamin D4 starts from ergosterol which is converted in 22,23-dhydroergosterol in six stages. The latter was irradiated to produce vitamin D4 which is converted, in four stages, to 1alpha-hydroxy vitamin D4 using a cyclovitamine procedure which produces the new intermediates, vitamin D4 tosylate, 3,5 cyclovitamine D4 and 1alpha- hydroxy cyclovitamin D4. 1.25 dihydroxy vitamin D4 and 1.24 dihydroxy vitamin D4 are isolated as biological products of the metabolism of the new 1alpha-hydroxy vitamin D4 using cultured human liver cells. |
| priorityDate | 1990-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 212.