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filingDate 1991-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1992-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0502213-A1
titleOfInvention Leukocyte removal method and leukocyte removal filter system
abstract A method of removing leukocytes from a leukocyte-containing blood preparation which comprises preparing a leukocyte-poor blood preparation by subjecting the leukocyte-containing blood preparation to the first-stage leukocyte removal treatment to remove at least 60 % of the leukocytes contained in said preparation and subjecting the leukocyte-poor blood preparation to the second-stage leukocyte removal treatment by the use of a microfilter element made from nonwoven or woven fabric having a mean fiber diameter of 0.3 to 1.6 µm. A leukocyte removal filter system wherein the first-stage filter element communicates with the second-stage filter element and is located on the upstream side of the second-stage element in the direction of flow of the leukocyte-containing blood preparation being treated. The above method and system can reduce the content of the leukocytes remaining in the blood preparation to 10⁻⁴ or below and also the size of the filter.
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