| abstract |
In a starting mixture containing the dextrorotatory and levorotatory enantiomers of methyl trans -2,3-epoxy-3- (4-methoxyphenyl) propionate, the dextrorotatory enantiomer is subjected to transesterification in an anhydrous medium, which transforms it into a derivative insoluble, in the presence of an enzyme which does not affect the levorotatory enantiomer. The latter is an intermediary for the synthesis of compounds such as Diltiazem. |