| abstract |
New trifluoromethylketone derivatives of the following formula :n whereinn R 1 is lower alkyl which has one or two substituents selected from carboxy, esterified carboxy and di-lower alkylcarbamoyl ; phenyl(lower)alkyl, the phenyl moiety of which may have halogen or nitro or amino and the alkyl moiety of which may have carboxy or esterified carboxy ; halo-phenyl ; morpholino ; or morpholino(lower)alkyl, R 2 and R 3 are each lower alkyl, X is - or -NH-, and Y isn and pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them. |